Research
Model for Management of Breastfeeding in Women with HIV in the U.S.
In this article, the authors describe an approach to managing care for breastfeeding women with HIV at a single large-volume site in the United States.
Citation:
Abuogi L, Smith C, Kinzie K. Development and implementation of an interdisciplinary model for the management of…
Best Practices for Infant Feeding for People with HIV in High Resource Settings
In this article, the authors set forth a multi-disciplinary approach for best practices to maximize risk reduction in infants whose birth parents choose to breast/chestfeed in high resource settings like the United States.
Citation:
Powell AM, Knott-Grasso MA, Anderson J, et al.…
Best Practices for Implementation of Breastfeeding for PWH
The authors describe the efforts at their institution to develop a structured shared decision-making process and protocol for successful implementation of breastfeeding for people living with HIV.Citation: Powell AM, Knott-Grasso MA, Anderson J et al., Infant feeding for people living with HIV in…
Perinatal HIV Transmission Is Being Eliminated in the U.S.
In this article, the authors from the Centers for Disease Control and Prevention describe progress toward elimination of perinatal HIV in the United States and document that the ambitious elimination goals in the United States were first met in 2019.
Citation:
Lampe MA,…
ARV Treatment During Pregnancy
This new JAMA article describes the availability, timing, and risks of antiretroviral therapy in pregnant people with HIV.
Citation:
Eke AC, Lockman S, Mofenson LM. Antiretroviral treatment of HIV/AIDS during pregnancy. JAMA. 2023 Apr 18;329(15):1308-1309. …
Mindfulness Intervention for Pregnant and Parenting WLWH
The authors describe their experience conducting focus groups to inform the adaptation of a mindfulness intervention for pregnant and parenting women living with HIV. They detail the focus group experience exploring psychosocial treatment needs and mindfulness intervention preferences. …
Importance of Timely Diagnosis of Perinatal HIV in Children
The authors present the case of a 6-year-old child with a delayed diagnosis of perinatal HIV infection. They describe the increased morbidity resulting from the delay and remind clinicians of the importance of universal HIV screening of pregnant women (including repeat third trimester testing),…
Disparities in Third Trimester Syphilis Testing in Illinois
The authors, including Hotline Co-Medical Director Dr. Lynn Yee, report on their findings regarding repeat third trimester syphilis testing at a large tertiary hospital in Chicago, Illinois. They observe overall low compliance with the state law mandating repeat third trimester testing and…
New Findings on the Use of Dolutegravir in Pregnancy
A recent comparative study in the New England Journal of Medicine reports on the benefits of Dolutegravir in pregnancy compared to other HIV regimens currently used in the United States.
Patel K, Huo Y, Jao J, et al. Dolutegravir in pregnancy as compared with current HIV regimens in the…
Mental Health in Women Living with HIV
In this review, the authors explore the unique mental health issues faced by women living with HIV and examine the feasibility and outcomes of mental health interventions that have been tested in this population.
Citation: Waldron EM, Burnett-Zeigler I, Wee V, Ng YW, Koenig LJ,…
Third Trimester Repeat HIV Testing: It's Time We Make it Universal
This clinical opinion piece is the Illinois Perinatal HIV Hotline team's call to action for universal repeat third trimester HIV testing as a key strategy toward perinatal HIV elimination.
Citation: Cassimatis IR, Ayala LD, Miller ES, Garcia PM, Jao J, Yee LM. Third trimester repeat…
Housing Instability and Virologic Control Among Pregnant Individuals with HIV
The authors, including many of the clinicians on the Illinois Perinatal HIV Hotline, examine the association between housing instability and HIV outcomes in pregnant individuals living with HIV.
Citation: Cassimatis IR, Miller ES, Benes L, Levesque J, Yee LM. Housing instability is…
Safety of Early Nevirapine Therapy for Neonates at High Risk for Perinatal HIV Infection
This study examined the pharmacokinetics and safety of nevirapine for use in the early neonatal period. The authors found that nevirapine at the dose studied was confirmed to be safe, and that the data support nevirapine as a component of presumptive HIV treatment in high-risk neonates.…
Communication About Partner HIV Testing in the U.S.
This qualitative study in a high HIV prevalence U.S. city explored communication about HIV testing among pregnant HIV-negative women and their male partners. The authors suggest future research is needed to assess specific barriers to male partner HIV testing as an approach to preventing…
Social Vulnerability among Foreign-Born Pregnant Women and Virologic Control of HIV
This study assessed the relationship between social vulnerability among foreign-born pregnant women living with HIV and maternal viremia during pregnancy. The authors found virologic control during pregnancy to be worse among socially-vulnerable women and recommend closer follow-up and…
Pregnancy Intention and Viral Suppression Among Pregnant Women with HIV
This study examines pregnancy intention and its relationship to achieving viral suppression by delivery. The authors found that women with an unintended pregnancy were less likely to be on antiretroviral therapy prior to initiating prenatal care and were less likely to be virally suppressed…
SMFM Releases Updated Checklists for Management of HIV in Pregnancy
The Society for Maternal-Fetal Medicine has published updated and expanded checklists to help ensure that all relevant elements are considered for every person with HIV during prepregnancy, antepartum, intrapartum, and postpartum periods. The checklists are intended to be used as tools to…
Data Support Nevirapine for Presumptive Treatment in High Risk Neonates
Recent findings from the IMPAACT P1115 study confirm the safety and therapeutic drug concentrations of a nevirapine-based antiretroviral regimen in the early neonatal period. The study's aim was to establish dosing of nevirapine for very early treatment of HIV-exposed neonates at high risk of…
Updated AAP Guidance for Infants Exposed to HIV
Updated in October 2020, this clinical report from the American Academcy of Pediatrics provides guidance on the evaluation and management of infants born to women living with HIV.
Citation: Chadwick EG. AAP Committee on Pediatric AIDS. Evaluation and management of the infant exposed to…
COVID-19 Among People Living with HIV
This issue of AIDS includes a special section on the intersection of COVID-19 and people living with HIV.
AIDS October 1, 2020 - Volume 34 - Issue 12
HIV PrEP for Conception Among Serodiscordant Couples
This article describes a prospective cohort study to assess the feasibility, perceptions, and adherence associated with periconceptional PrEP use among females without HIV and their male partners living with HIV across four academic medical centers in the United States.
Citation: Leech AA,…
Attitudes Towards Male Partner HIV Testing
This study, by members of the Illinois Perinatal HIV Hotline medical leadership team, explores the attitudes of pregnant women and their partners toward partner HIV testing.
Citation: Yee LM, Leziak K, Jackson J, Miller ES. Attitudes towards male partner HIV testing among…
Safety of In-Utero ARV Exposure
A recent study of neurological outcomes in children who are HIV-exposed but uninfected found some increased risk of neurologic abnormalities. These risks were associated with exposure to efavirenz and didanosine. Dolutegravir expsoure showed some suggestive associations that the authors suggest…
Epidemiology of Perinatal HIV Transmission in the U.S.
This article examines the most recent epidemiology of perinatal HIV transmission in the United States in the era of elimination. It looks at the perinatal HIV prevention cascade, annual births to women with HIV, the population of women living with HIV, and their geographical distribution…
Reproductive Years of Women with Perinatally Acquired HIV
This article, written by members of the IL Perinatal HIV Hotline team, reviews existing evidence regarding the gynecologic and obstetric issues unique to reproductive age women with perinatally acquired HIV.
Citation:
Berhie S, Yee L, Jao J. The reproductive years of women with…