HIV-infected infants that are started on ARVs early show low levels of replication-competent provirus, an absence of HIV-specific immunity, and the capacity to generate immune responses to potential immunotherapeutic interventions according to recent research. Current studies are examining ways to keep perinatally-infected infants from having to be on ARVs for the remainder of their lives.
Citation:
Rainwater-Lovett K, Uprety P, Persaud D. Advances and hope for perinatal HIV remission and cure in children and adolescents. Curr Opin Pediatr. 2016 Feb;28(1):86-92.
Original Article (subscription may be required)